Anoctamin-1

An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.

Also Known As:

TMEM16A Protein; Transmembrane Protein 16A; Anoctamin 1

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Chloride Channels: 1813
        Anoctamins: 92
        Anoctamin-1: 100
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Ion Channels: 6936
        Chloride Channels: 1813
        Anoctamins: 92
        Anoctamin-1: 100
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Chloride Channels: 1813
        Anoctamins: 92
        Anoctamin-1: 100

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Disease

Drug/Important Bio-Agent (IBA)